Parents of infant who died in wrong-way crash on Ontario's Hwy. 401 were in same vehicle
Ontario’s Special Investigations Unit has released new details about a wrong-way collision in Whitby on Monday night that claimed the lives of four people.
Pfizer's updated COVID-19 booster significantly revved up adults' virus-fighting antibodies, the company said Friday, releasing early findings from a rigorous study of the new shots.
Booster doses tweaked to target the most common omicron strain rolled out in early September, and the Food and Drug Administration said the latest data should spur more Americans to get one -- especially before another expected wave of cases as people travel for Thanksgiving.
Pfizer said people 55 and older who got the omicron-targeting booster had four-fold higher antibody levels than those given an extra dose of the original vaccine.
With many Americans reluctant to roll up their sleeves again, perhaps the better question is how the new booster compares to going without another dose.
A hint: A month after receiving the new booster, antibody levels in people 55 and older had jumped 13 times higher than before the extra dose. Younger adults saw a 9.5-fold jump, Pfizer and its partner BioNTech said. It had been about 11 months since the study participants' last vaccination.
It's too soon to know how much real-world protection the antibody boost translates into -- and how long it will last. The results are preliminary, the study is still underway and infection-fighting antibodies naturally wane over time.
Still, the FDA had cleared the updated boosters without first requiring testing in people, basing the decision on studies of a similarly tweaked vaccine -- against an earlier omicron strain -- rather than the exact recipe.
So the new data "reassures us that this was a good decision to move to this bivalent vaccine," FDA vaccine chief Dr. Peter Marks told The Associated Press. "Right now is the time for people to consider going out and get the updated" booster.
Health experts say it's shaping up to be a rough winter. Flu season is starting unusually early and harsh, children's hospitals are packed with another respiratory illness named RSV, and COVID-19 cases again are expected to rise with holiday gatherings.
The original COVID-19 vaccines still offer strong protection against severe illness and death, especially among younger and healthier people who've gotten at least one booster -- a reason for anyone who hasn't gotten their first set of shots to do so. But effectiveness drops as new mutants emerge and more time passes since someone's last shot.
The updated doses are combination shots, tailored to offer a boost of protection against both the original coronavirus strain and the dominant BA.5 strain. Pfizer's shot is available for anyone 5 or older. Moderna's version of the updated booster is for those 6 and older.
About 26.3 million Americans have gotten an updated booster since they rolled out in early September, according to the Centers for Disease Control and Prevention.
Some small studies have recently raised questions about how much advantage the updated boosters will offer rather than just getting another dose of the original vaccine.
Pfizer's early findings compared several dozen younger and older adults given the bivalent booster with a group who received a fourth dose of the company's original vaccine.
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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Department of Science Education. The AP is solely responsible for all content
Ontario’s Special Investigations Unit has released new details about a wrong-way collision in Whitby on Monday night that claimed the lives of four people.
Three men in Quebec from the same family have fathered more than 600 children.
A British Columbia mayor has been censured by city council – stripping him of his travel and lobbying budgets and removing him from city committees – for allegedly distributing a book that questions the history of Indigenous residential schools in Canada.
A spike in impaired driving-related collisions has caused Ontario’s provincial police to begin enforcing mandatory alcohol screening (MAS) at all traffic stops in the Greater Toronto Area -- a move one civil rights group says is ‘not acceptable.’
William Nylander scored twice and Joseph Woll made 22 saves as the Toronto Maple Leafs downed the Boston Bruins 2-1 on Thursday to force Game 7 in their first-round series.
Jurors in the hush money trial of Donald Trump heard a recording Thursday of him discussing with his then-lawyer and personal fixer a plan to purchase the silence of a Playboy model who has said she had an affair with the former president.
Staff at a small southern Alberta office supply store were shocked to find someone had broken into the business last week, but they were even more confused when they discovered the culprit was a bear.
A federal judge on Thursday sentenced a scuba dive boat captain to four years in custody and three years supervised release for criminal negligence after 34 people died in a fire aboard the vessel.
Fake text message and email campaigns trying to get money and information out of unsuspecting Canadian taxpayers have started circulating, just months after the federal government rebranded the carbon tax rebate the Canada Carbon Rebate.
Three men in Quebec from the same family have fathered more than 600 children.
A group of SaskPower workers recently received special recognition at the legislature – for their efforts in repairing one of Saskatchewan's largest power plants after it was knocked offline for months following a serious flood last summer.
A police officer on Montreal's South Shore anonymously donated a kidney that wound up drastically changing the life of a schoolteacher living on dialysis.
Since 1932, Montreal's Henri Henri has been filled to the brim with every possible kind of hat, from newsboy caps to feathered fedoras.
Police in Oak Bay, B.C., had to close a stretch of road Sunday to help an elephant seal named Emerson get safely back into the water.
Out of more than 9,000 entries from over 2,000 breweries in 50 countries, a handful of B.C. brews landed on the podium at the World Beer Cup this week.
Raneem, 10, lives with a neurological condition and liver disease and needs Cholbam, a medication, for a longer and healthier life.
The lawyer for a residential school survivor leading a proposed class-action defamation lawsuit against the Catholic Church over residential schools says the court action is a last resort.
Mounties in Nanaimo, B.C., say two late-night revellers are lucky their allegedly drunken antics weren't reported to police after security cameras captured the men trying to steal a heavy sign from a downtown business.