BREAKING Slovak interior minister says 'lone wolf' has been charged with shooting prime minister
The Slovak interior minister said Thursday that a 'lone wolf' has been charged in the shooting that seriously wounded Prime Minister Robert Fico.
The U.S. Food and Drug Administration issued an emergency use authorization Tuesday that allows health-care providers to change how the Jynneos monkeypox vaccine is administered, stretching out the supply amid high demand.
The vaccine can now be given to high-risk adults intradermally, meaning between the layers of the skin, rather than subcutaneously, or under the skin, as it has been given up till now. This will allow providers to get five doses out of a standard one-dose vial.
The new EUA also allows subcutaneous vaccination in people under 18 who are at high risk of infection.
"In recent weeks the monkeypox virus has continued to spread at a rate that has made it clear our current vaccine supply will not meet the current demand," FDA Commissioner Dr. Robert M. Califf said in a statement. "The FDA quickly explored other scientifically appropriate options to facilitate access to the vaccine for all impacted individuals. By increasing the number of available doses, more individuals who want to be vaccinated against monkeypox will now have the opportunity to do so."
The move comes less than a week after the Biden administration declared monkeypox a public health emergency, which gives the FDA and other government health agencies more flexibility to fight the spread of the virus.
Earlier Tuesday, U.S. Department of Health and Human Services Secretary Xavier Becerra issued a determination to pave the way for the FDA's move.
"Last week, I declared monkeypox to be a public health emergency to unlock additional tools that will help us contain and end this outbreak and to signal to the American people that we are taking our response to the next level," Becerra said in a statement. "Today's action will allow FDA to exercise additional authorities that may increase availability of vaccines to prevent monkeypox while continuing to ensure the vaccine meets high standards for safety, effectiveness and manufacturing quality."
As of Monday, the US government has shipped 617,693 doses of Jynneos to states and jurisdictions. The US Centers for Disease Control and Prevention has estimated that at least 1.5 million people in the US are eligible for monkeypox vaccination.
As of Monday evening, the CDC reports 8,934 probable or confirmed monkeypox cases in 49 states, Puerto Rico and the District of Columbia.
With an intradermal vaccination, "basically, you're staying in the skin; you're not going through the skin," said Dr. Daniel Griffin, an infectious disease specialist at Columbia University.
Using a smaller dose with intradermal injection has been done with vaccines for flu and rabies, epidemiologist Dr. Jay Varma told CNN in an email.
"The skin has special cells that are very good at helping a vaccine stimulate the body's immune system," he wrote.
These cells, called dendritic cells, are better able to produce an immune response, Griffin said.
"They live in the skin, and they're better at teaching the immune system what they need to respond to," he said.
"If you're able to give the monkeypox vaccine intradermally, you can give a smaller dose. ... They just would need to have some sort of demonstration that you get the same immune response," he said.
The Slovak interior minister said Thursday that a 'lone wolf' has been charged in the shooting that seriously wounded Prime Minister Robert Fico.
Although a global workers' treaty has been in force in Canada since January, an employment lawyer believes it won't do anything more to protect employees from violence and harassment.
The Saskatchewan RCMP wants you to know it’s not targeting drive-thrus to ticket people for using their fast food reward apps.
Auto technology has evolved and many newer cars use wireless key fobs and push-button starters instead of traditional metal keys. But that technology also makes things easier for thieves.
Air quality warnings are still in place for some areas of Western Canada, according to the latest forecasts.
Thousands of Canadians have been displaced as fires burn in Alberta, B.C. and Manitoba. Here are the latest updates.
With prosecutors' hush money case against Donald Trump barreling toward its end, their star witness will be back in the hot seat Thursday as defense lawyers try to chip away at Michael Cohen's crucial testimony implicating the former president.
Canada's transportation department had a UFO 'lead' who tried to 'quell' media interest and planned to meet with U.S. intelligence officials.
Regaining your focus requires you to be mindful of how you are using technology -- a daunting task if you consider the average American spends at least 10 hours a day on screens.
When Adam Kirschner wrote 'Slap Shot,' he never imagined the song would be embraced by his favourite team.
A team is ready to help an entangled North Atlantic right whale in the Gulf of St. Lawrence.
A $200 reward is being offered by a North Vancouver family for the safe return of their beloved chicken, Snowflake.
Two daughters and a mother were reunited online 40 years later thanks to a DNA kit and a Zoom connection despite living on three separate continents and speaking different languages.
Mother's Day can be a difficult occasion for those who have lost or are estranged from their mom.
YES Theatre Young Company opened its acclaimed kids’ show, One Small Step, at Sudbury Theatre Centre on Saturday.
An Ottawa pizzeria is being recognized as one of the top 20 deep-dish pizzas in the world.
A family of fifth generation farmers from Ituna, Sask. are trying to find answers after discovering several strange objects lying on their land.
A Listowel, Ont. man, drafted by the Hamilton Tigercats last week, is also getting looks from the NFL, despite only playing 27 games of football in his life.