Signs of Alzheimer’s were everywhere. Then his brain improved
Blood biomarkers of telltale signs of early Alzheimer’s disease in the brain of his patient, 55-year-old entrepreneur Simon Nicholls, had all but disappeared in a mere 14 months.
“How much plastic will you have for dinner, sir? And you, ma’am?” While that may seem like a line from a satirical skit on Saturday Night Live, research is showing it’s much too close to reality.
Ninety per cent of animal and vegetable protein samples tested positive for microplastics, teeny polymer fragments that can range from less than five millimeters down to one micrometer, according to a February 2024 study. Anything smaller than one micrometer is a nanoplastic that must be measured in billionths of a meter.
Even vegetarians can’t escape, according to a 2021 study. If the plastic is small enough, fruits and vegetables can absorb microplastics through their root systems and transfer those chemical bits to the plant’s stems, leaves, seeds and fruit.
Salt can be packed with plastic. A 2023 study found coarse Himalayan pink salt mined from the ground had the most microplastics, followed by black salt and marine salt. Sugar is also “an important route of human exposure to these micropollutants,” according to a 2022 study.
Even tea bags, many of which are made of plastic, can release enormous amounts of plastic. Researchers at McGill University in Quebec, Canada found brewing a single plastic teabag released about 11.6 billion microplastic and 3.1 billion nanoplastic particles into the water.
Rice is also a culprit. A University of Queensland study found that for every 100 grams (1/2 cup) of rice people eat, they consume three to four milligrams of plastic — the number jumps to 13 milligrams per serving for instant rice. (You can reduce plastic contamination by up to 40 per cent by washing rice, researchers said. That also helps reduce arsenic, which can be high in rice.)
Let’s not forget bottled water. One liter of water — the equivalent of two standard-size bottled waters — contained an average of 240,000 plastic particles from seven types of plastics, including nanoplastics, according to a March 2024 study.
While microplastics have been found in the human lung, maternal and fetal placental tissues, human breast milk and human blood, until recently there was very little research on how these polymers affect the body’s organs and functions.
A March 2024 study found people with microplastics or nanoplastics in arteries in the neck were twice as likely to have a heart attack, stroke or die from any cause over the next three years than people who had none.
Nanoplastics are the most worrisome type of plastic pollution for human health, experts say. That’s because the minuscule particles can invade individual cells and tissues in major organs, potentially interrupting cellular processes and depositing endocrine-disrupting chemicals such as bisphenols, phthalates, flame retardants, per- and polyfluorinated substances, or PFAS, and heavy metals.
“All of those chemicals are used in the manufacturing of plastic, so if a plastic makes its way into us, it’s carrying those chemicals with it,” Sherri “Sam” Mason, director of sustainability at Penn State Behrend in Erie, Pennsylvania, told CNN in a prior interview.
“And because the temperature of the body is higher than the outside, those chemicals are going to migrate out of that plastic and end up in our body,” Mason said.
“Those chemicals can be carried to your liver and your kidney and your brain and even make their way across the placental boundary and end up in an unborn child,” she said.
“There currently is no scientific consensus on the potential health impacts of nano- and microplastic particles. Therefore, media reports based on assumptions and conjecture do nothing more than unnecessarily scare the public,” a spokesperson for the International Bottled Water Association, an industry association, told CNN previously.
In the February study, which was published in Environmental Research, researchers looked at over a dozen commonly consumed proteins, including beef, breaded and other types of shrimp, chicken breasts and nuggets, pork, seafood, tofu and several plant-based meat alternatives, such as nuggets, plant crumbles similar to ground beef and plant-based fish sticks.
Breaded shrimp contained the most tiny plastics by far, at well over an average of 300 microplastic pieces per serving. Plant-based nuggets came in second, at under 100 pieces per serving, followed by chicken nuggets, pollock fish sticks, minimally processed White Gulf shrimp, fresh caught Key West pink shrimp and a plant-based fish-like stick.
The least contaminated proteins were chicken breasts, followed by pork loin chops and tofu.
After comparing the results to consumer consumption data, researchers estimated the average exposure of American adults to microplastics could range between 11,000 and 29,000 particles a year, with a maximum estimated exposure of 3.8 million microplastics per year.
The oceans are filled with plastics, and a number of studies have captured how those are ending up in the seafood we eat. However, fewer studies have looked at vegetables and land animal proteins, such as cattle and hogs, according to an August 2020 study.
The study, published in Environmental Science, found between 52,050 and 233,000 plastic particles under 10 micrometers — each micrometer is about the diameter of a rain drop — in a variety of fruits and vegetables.
Apples and carrots were the most contaminated fruit and vegetable, respectively, with over 100,000 microplastics per gram. The smallest particles were found in carrots, while the largest pieces of plastic were found in lettuce, which was also the least contaminated vegetable.
There are a staggering number of plastics in the world, today, according to a recent analysis — 16,000 plastic chemicals, with at least 4,200 of those considered to be “highly hazardous” to human health and the environment.
As these chemicals break down in the environment, they can turn into microplastics and then nanoplastics, particles so small science struggled for decades to see them.
A recent study that utilized brand new technology found the number of nanoplastics in three popular brands of water sold in the United States to be in between 110,000 and 370,000 per liter, if not higher. A liter is the equivalent of about two 16 ounce bottled waters. (The authors declined to mention which brands of bottled water they studied.)
Prior research using older technology had identified only about 300 nanoplastics in bottled water, along with bigger microplastics.
The levels of contamination found in bottled water reinforce long-held expert advice to drink tap water from glass or stainless steel containers to reduce exposure, Mason said. That advice extends to other foods and drinks packaged in plastic as well, she added.
“People don’t think of plastics as shedding but they do,” she said. “In almost the same way we’re constantly shedding skin cells, plastics are constantly shedding little bits that break off, such as when you open that plastic container for your store-bought salad or a cheese that’s wrapped in plastic.”
While science learns more about the plastics we consume, there are things people can do to reduce their exposure, according to experts.
Blood biomarkers of telltale signs of early Alzheimer’s disease in the brain of his patient, 55-year-old entrepreneur Simon Nicholls, had all but disappeared in a mere 14 months.
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