Motorists can expect some significant road closures in the downtown core this weekend to accommodate fundraising events. Bike for Brain Health Both the Gardiner Expressway and the Don Valley Parkway will be closed on Sunday for the Bike for Brain Health event. The city says the two highways will be closed from 12:01 a.m. to 4 p.m. for the charity bike ride. All eastbound traffic on the Gardiner will exit onto Lake Shore Boulevard West at Humber River. We Walk UHNited event The first annual We Walk UHNited event will be held on Saturday, resulting in a number of road closures downtown. The following road closures will be in place from 8 a.m. to 1 p.m. to accommodate the walk, which includes both two-kilometre and five-kilometre routes. “Those who need to travel near road closures should plan their travel in advance, allow for extra time, consider taking public transit or other travel methods such as walking or cycling and follow signage to keep everyone safe,” the city said in a news release.