Indian envoy warns of 'big red line,' days after charges laid in Nijjar case
India's envoy to Canada insists relations between the two countries are positive overall, despite what he describes as 'a lot of noise.'
Researchers at Brigham and Women’s Hospital in Boston are testing an Alzheimer's vaccine on people.
The nasally administered vaccine, called Protollin, is being tested on a group of 16 people with early Alzheimer's disease, between the ages of 60 to 85 years.
Alzheimer's is a cognitive disease that impairs a memory, thought, and language. It is the most common type of dementia. In 2020, 569,600 Canadians were living with dementia.
"This (vaccine) is using some proteins to stimulate the body's own immune cells to clear away the beta-amyloid, which is really the problematic protein in Alzheimer's disease," Dr. Tanuja Chitnis, a neurologist with Brigham and Women’s Hospital, told CTV's Your Morning on Friday.
Amyloid is a protein that builds up in organs and can affect the heart, kidneys, liver, and nervous system.
The vaccine is showing positive results, but more testing is needed to understand dosages and any implications.
"We found that this drug is safe and well-tolerated," Chitnis said. "We're currently working on immunological studies to prove that the vaccine works in the way that we think it does."
If successful, this vaccine could drastically change the lives of people living with Alzheimer's, Chitnis said, allowing anyone to easily administer the drug. The Alzheimer Society of Canada says about 1 in 5 people have experienced caring for someone living with dementia.
"Our results suggested quite safe and patients with early Alzheimer's disease, and we're hoping that it will prevent patients from progressing into those later and more problematic stages of disease in which they can't take care of themselves," Chitnis said.
Another Alzheimer's vaccine has concluded trial results from the U.K., where a randomized placebo-controlled study showed there was a 27 per cent less decline in memory after 18 months.
Chitnis believes more research on Alzheimer's vaccines is "very exciting."
"We're seeing a lot of new treatments for Alzheimer's disease," she said. "Our approach is somewhat different, again, using the body's own immune cells to actually activate and clear away amyloid."
When asked about the trial, Joshua Armstrong, a research scientist with the Alzheimer Society of Canada, said the group would be watching for results.
"This vaccine-like approach of using a nasal spray to activate the body's immune system is a novel and innovative way of potentially addressing the beta amyloid plaques that build up in the brains of people living with Alzheimer's disease," Armstrong said in an email to CTVNews.ca Friday.
"If this treatment passes this Phase 1 trial, which examines the safety and tolerability in just 16 individuals with early-stage Alzheimer's disease, we will be following the future trials of Protollin to see if they result in the reduction of amyloid plaques and the slowing or reversal of cognitive decline in a larger group of patients."
India's envoy to Canada insists relations between the two countries are positive overall, despite what he describes as 'a lot of noise.'
With Donald Trump sitting just feet away, Stormy Daniels testified Tuesday at the former president's hush money trial about a sexual encounter the porn actor says they had in 2006 that resulted in her being paid to keep silent during the presidential race 10 years later.
The U.S. paused a shipment of bombs to Israel last week over concerns that Israel was approaching a decision on launching a full-scale assault on the southern Gaza city of Rafah against the wishes of the U.S.
Footage from dozens of security cameras in the area of Drake’s Bridle Path mansion could be the key to identifying the suspect responsible for shooting and seriously injuring a security guard outside the rapper’s sprawling home early Tuesday morning, a former Toronto homicide detective says.
A chicken farmer near Mattawa made an 'eggstraordinary' find Friday morning when she discovered one of her hens laid an egg close to three times the size of an average large chicken egg.
Susan Buckner, best known for playing peppy Rydell High School cheerleader Patty Simcox in the 1978 classic movie musical 'Grease,' has died. She was 72.
Accused killer Jeremy Skibicki could have a challenging time convincing a judge that he is not criminally responsible for the deaths of four Indigenous women, a legal analyst says.
A Calgary bylaw requiring businesses to charge a minimum bag fee and only provide single-use items when requested has officially been tossed.
Two Nova Scotia men are dead after a boat they were travelling in sank in the Annapolis River in Granville Centre, N.S., on Monday.
An Ontario man says he paid more than $7,700 for a luxury villa he found on a popular travel website -- but the listing was fake.
Whether passionate about Poirot or hungry for Holmes, Winnipeg mystery obsessives have had a local haunt for over 30 years in which to search out their latest page-turners.
Eighty-two-year-old Susan Neufeldt and 90-year-old Ulrich Richter are no spring chickens, but their love blossomed over the weekend with their wedding at Pine View Manor just outside of Rosthern.
Alberta Ballet's double-bill production of 'Der Wolf' and 'The Rite of Spring' marks not only its final show of the season, but the last production for twin sisters Alexandra and Jennifer Gibson.
A mother goose and her goslings caused a bit of a traffic jam on a busy stretch of the Trans-Canada Highway near Vancouver Saturday.
A British Columbia mayor has been censured by city council – stripping him of his travel and lobbying budgets and removing him from city committees – for allegedly distributing a book that questions the history of Indigenous residential schools in Canada.
Three men in Quebec from the same family have fathered more than 600 children.
A group of SaskPower workers recently received special recognition at the legislature – for their efforts in repairing one of Saskatchewan's largest power plants after it was knocked offline for months following a serious flood last summer.
A police officer on Montreal's South Shore anonymously donated a kidney that wound up drastically changing the life of a schoolteacher living on dialysis.