Highway 6 in northern Ontario between Espanola and Manitoulin Island reopened Thursday evening following a serious two-vehicle collision. The road was closed in both directions from Hopkins Hill Road and Merritt Township Road in Espanola around 11 a.m., according to a social media post by the Ministry of Transportation. Two vehicles, a passenger vehicle and a commercial box van, were involved in the crash that injured four people, Ontario Provincial Police Const. Berkley Parisien told CTVNewsNorthernOntario.ca in a phone interview. The extent of the injuries is still being determined, but one person was airlifted by an ORNGE Air ambulance. There is no word yet on whether any charges are pending in connection with the crash, but the investigation is in its early stages and will continue.