KANSAS CITY, Mo. -- Ian Kennedy pitched impressively into the seventh inning in his Kansas City debut and the Royals hit their first three home runs of the season to beat the winless Minnesota Twins 7-0 Saturday night.

The Twins fell to 0-5 for the first time since the Washington Senators moved to Minnesota in 1961.

Kennedy (1-0), signed by the Royals to a five-year $70 million contract in January, limited the Twins to five hits -- including four singles, before being pulled after 109 pitches with two out in the seventh.

Mike Moustakas and Lorenzo Cain hit successive home runs in the fourth for the first hits off Twins left-hander Tommy Milone, while Kendrys Morales homered in the sixth off Casey Fien.

Milone (0-1) allowed four runs and four hits in 4 2/3 innings.

PHILLIES 1, METS 0

NEW YORK (AP) -- Vince Velasquez struck out a career-high nine over six innings in his Philadelphia debut, Ryan Howard homered off Bartolo Colon and the Phillies got their first win this season.

Velasquez (1-0), a 23-year-old right-hander acquired in the seven-player off-season deal that sent closer Ken Giles to Houston, struggled through a 26-pitch first inning but retired Neil Walker on an inning-ending flyout with two on. New York didn't put two runners on in an inning after that.

Velasquez made seven starts and 12 relief appearances as a rookie last year. Helping the rebuilding Phillies avoid what would have been their first 0-5 start since 1934, he gave up three hits and three walks.

Hector Neris, Daniel Stumpf, David Hernandez and Jeanmar Gomez combined for hitless relief, sealing just the second win for the Phillies in their last 12 games at Citi Field. Gomez got three outs for his second career save, his first since July 2014 with Pittsburgh.

YANKEES 8, TIGERS 4

DETROIT (AP) -- CC Sabathia pitched into the seventh inning in his return for New York, and Alex Rodriguez and Carlos Beltran homered in the cold to lift the Yankees past Detroit.

Sabathia (1-0) allowed three runs and four hits in six-plus innings in his first start since missing the post-season last year while undergoing alcohol rehabilitation. He retired the first nine batters he faced and had only one really messy stretch, in the fourth. Rodriguez gave the Yankees a 1-0 lead in the first with his 688th career homer, and Beltran hit a two-run shot in the fifth.

Mike Pelfrey (0-1) allowed six runs and eight hits in 3 2/3 innings in his first start for the Tigers after signing with Detroit in the off-season.

The temperature at game time was 31 degrees, the coldest in Comerica Park history, according to STATS.

DODGERS 3, GIANTS 2

SAN FRANCISCO (AP) -- Madison Bumgarner hit another home run off Dodgers star Clayton Kershaw, but both aces were done by the time Charlie Culberson hit a go-ahead double in the 10th inning to lift Los Angeles over San Francisco.

Chris Hatcher (1-0) retired pinch-hitter Joe Panik on a called third strike to send the game into extras, then Kenley Jansen finished for his second save. The Dodgers were on the other side of a 3-2 result in 10 innings a night earlier.

Bumgarner struck out eight and Kershaw had five Ks in his eight innings for another impressive duel between the ace left-handers.

Bumgarner hit a solo homer off Kershaw in the second inning, his second in two seasons against his National League West rival.

George Kontos (0-1) gave up a one-out double to Corey Seager before Culberson's extra-base hit.

ASTROS 6, BREWERS 4

MILWAUKEE (AP) -- Colby Rasmus hit two home runs and a sacrifice fly to lead the Houston Astros past the Milwaukee Brewers 6-4 Saturday night.

Rasmus teed off on Milwaukee starter Wily Peralta (0-2) with a solo shot in the third and a two-run blast in the fifth that landed near the top row of the second-tier bleachers in right.

Rasmus may have found some motivation after being called for interference under the new "Chase Utley rule," resulting in a game-ending double play Friday night that halted Houston's ninth-inning rally and gave the Brewers a 6-4 win.

Tyler White kept up his torrid start for Houston with a sacrifice fly in the first and followed Rasmus in the fifth with his third home run. White is 10 for 15 (.667) so far in his rookie season.

Doug Fister (1-0) won his Astros' debut, allowing three runs on five hits in five innings.

RED SOX 8, BLUE JAYS 4.

TORONTO (AP) -- Dustin Pedroia had three hits and two RBIs and Rick Porcello pitched six innings to win his season debut to lead Boston.

Jose Bautista hit a pair of two-run home runs, his first two of the season, but the Blue Jays lost their fourth straight.

Hanley Ramirez tripled home the tiebreaking run on a ball that bounced over Bautista's head in the fifth. Ramirez later scored on a passed ball.

The Red Sox have scored at least six runs and finished with at least 10 hits in all four games this season, the third time in team history they've done so.

Porcello (1-0) allowed four runs and seven hits in six innings. Kojie Uehara worked the seventh and Robbie Ross Jr. handled the final two innings.

R.A. Dickey (1-1) allowed seven runs, six earned, and eight hits in five innings.

REDS 5, PIRATES 1

CINCINNATI (AP) -- Eugenio Suarez drove in three runs with a single and a homer, and ace-by-default Raisel Iglesias made another solid start as Cincinnati handed Pittsburgh its firt loss.

At 4-0, Pittsburgh was off to its best start since 2003. The Pirates also had their top starter making his debut -- Gerrit Cole (0-1) was pushed back in the rotation after developing a sore ribcage during spring training. He still couldn't beat the Reds, falling to 0-5 in seven starts against them.

Suarez had an RBI single in the first and a two-run homer in the seventh -- his team-leading third of the season. He also scored three times.

Iglesias (1-0) gave up a run and eight hits in 5 2/3 innings. He was moved to the front of the rotation when injuries sent four starters to the disabled list.

WHITE SOX 7, INDIANS 3

CHICAGO (AP) -- Avisail Garcia hit a three-run home run in the decisive seventh inning, ace Chris Sale overcame two home runs to stay unbeaten and Chicago rallied past Cleveland.

Garcia, picked off first base a day earlier in a miserable home opener for the White Sox, went the opposite way off Bryan Shaw (0-1). Melky Cabrera's nine-pitch RBI single a batter earlier put the White Sox ahead.

Jose Abreu hit a solo home run and reached base four times, while Sale (2-0) allowed three runs and six hits with six strikeouts in seven innings in the White Sox's fourth win in six games.

Sale had retired 12 straight before an infield single and Mike Napoli's two-run homer to centre in the sixth tied it. Yan Gomes' solo shot an inning later put the Indians ahead before Chicago's five-run seventh.

CUBS 4, DIAMONDBACKS 2

PHOENIX (AP) -- Arizona ace Zack Greinke got off to a rough start and lost again, with Kris Bryant and Chicago beating the Diamondbacks.

Greinke (0-2) gave up three runs in the first inning on four consecutive hits and a sacrifice fly.

Greinke signed a $206.5 million, six-year deal with the Diamondbacks as a free agent after going 19-3 with a 1.66 ERA for the Dodgers last season. Hit hard by Colorado on opening day earlier this week, the right-hander now has a 9.90 ERA.

Bryant doubled twice and Ben Zobrist had three hits for the Cubs.

Kyle Hendricks (1-0) pitched four-hit ball into the seventh inning.

CARDINALS 12, BRAVES 2

ATLANTA (AP) -- Pitcher Carlos Martinez drove in two runs, matching the total he allowed in six innings, and St. Louis beat Julio Teheran and winless Atlanta.

At 0-4, Atlanta is the only NL team without a victory this season.

Martinez (1-0) allowed two runs on four hits and three walks.

The Cardinals have scored a combined 19 runs while winning the first two games of the weekend series. They were held to only seven runs in three losses at Pittsburgh to open the season.

Kolten Wong had three hits, scored two runs and also reached on one of Atlanta's two errors. Aledmys Diaz had two hits, including an RBI off John Gant in the eighth.

Teheran (0-1) gave up four earned runs on six hits and four walks in four innings. He also threw two wild pitches.