Man-made chemicals found in industrial products, commonly referred to as “forever chemicals,” have been linked to the most common type of liver cancer, a new study has found.
Polyfluoroalkyl substances (PFAS) are called “forever chemicals” because they last so long in the environment and are hard to break down. They pollute the atmosphere and can affect organ tissues in exposed animals and humans.
Researchers at the University of Southern California gathered data from human blood and tissue samples of more than 200,000 residents in Los Angeles and Hawaii to study the development of cancer or other diseases. Through their data they found 50 people who eventually developed liver cancer and compared their samples before diagnosis to 50 other participants who did not develop the disease.
Blood samples taken from the cancer patients prior to their diagnoses contained several types of PFAS, specifically, perfluorooctane sulfate (PFOS) a class of PFAS. The study found that patients in the top 10 per cent of PFOS exposure were more likely to develop non-viral hepatocellular carcinoma, the most common type of liver cancer, in comparison to those with lower percentage levels of the chemicals in their blood samples.
The study concludes that PFOS can disrupt the metabolic process in the liver which affects the process of glucose metabolism, bile acid metabolism and branched chain amino acids. Abnormal metabolic processes in the liver can lead to non-alcoholic fatty liver disease (NAFLD), the study says, which has become concerning as cases of NAFLD have increased across the world in recent years.
While past studies have indicated how harmful these chemicals can be to animals, researchers of this study say the new evidence from human samples is a step forward to understanding the graver consequences of exposure to PFAS.
“We believe our work is providing important insights into the long-term health effects that these chemicals have on human health, especially with respect to how they can damage normal liver function,” lead researcher Leda Chatzi said in a news release.
Police say one former and one current employee of Air Canada are among the nine suspects that are facing charges in connection with the gold heist at Pearson International Airport last year.
Drivers in Eastern Canada face a big increase in gas prices because of various factors, especially the higher cost of the summer blend, industry analysts say.
Several Tim Horton’s customers are feeling great disappointment after being told by the company that an email stating they won a boat worth nearly $60,000 was sent in error.
Toronto Raptors player Jontay Porter has been handed a lifetime ban from The National Basketball Association (NBA) following an investigation which found he disclosed confidential information to sports bettors, the league says.
The RCMP confirmed Wednesday it had executed a search warrant at an address registered to GC Strategies. This development comes as MPs are enacting an extraordinary, rarely used parliamentary power, summoning one of its contractors to appear before the House of Commons to be admonished publicly for failing to answer questions related to the ArriveCan app.
A woman who pressured her boyfriend into killing his teenage ex more than a decade ago will be allowed to leave prison for weeks at a time.
A motion filed by the man accused of killing four Indigenous women in Winnipeg to have one of those murder charges quashed has been dismissed by the judge – weeks before the start of his trial.
In their 2024 budget, the federal government wants to amend the Canada Labour Code, so employers in federally regulated sectors will eliminate work-related communication with employees outside of scheduled hours. If implemented, this would affect roughly 500,000 across the country.
An earthquake with a preliminary magnitude of 6.4 hit southern Japan late on Wednesday, said the Japan Meteorological Agency, without issuing a tsunami warning.
Almost 7,000 bars of pure gold were stolen from Pearson International Airport exactly one year ago during an elaborate heist, but so far only a tiny fraction of that stolen loot has been found.
Video of the moment a suspect left Toronto Pearson International Airport with more than $22 million in gold and cash has been released by police.
Prosecutors and defence lawyers are expected to make their final submissions today in the trial of a man accused of running over a Toronto police officer.
Progress has been made on a new compensation model for family doctors, with the Alberta Medical Association (AMA) hopeful for a fall rollout.
Several Tim Horton’s customers are feeling great disappointment after being told by the company that an email stating they won a boat worth nearly $60,000 was sent in error.
A motion filed by the man accused of killing four Indigenous women in Winnipeg to have one of those murder charges quashed has been dismissed by the judge – weeks before the start of his trial.
The U.S. Senate killed the articles of impeachment against Homeland Security Secretary Alejandro Mayorkas on Wednesday as the historic trial of the Cabinet secretary barely got underway.
The United Nations Security Council is scheduled to vote Friday on a Palestinian request for full UN membership, said diplomats, a move that Israel ally the United States is expected to block because it would effectively recognize a Palestinian state.
Uber is helping investigators lookin into the account that sent a driver to the Ohio home where an 81-year-old man allegedly shot the woman to death because he erroneously believed she was part of a scam, the ride-hailing company said Wednesday.
An investigation of the catastrophic Maui wildfires that killed 101 people, destroyed hundreds of homes and left US$6 billion in damages reveals a spate of problems with emergency preparation and coordination before and during the disaster.
The sound of a vehicle backfiring spooked a circus elephant while she was getting a pre-show bath in Butte, Montana, leading the pachyderm to break through a fence and take a brief walk, stopping noontime traffic on the city's busiest street before being loaded back into a trailer.
An earthquake with a preliminary magnitude of 6.4 hit southern Japan late on Wednesday, said the Japan Meteorological Agency, without issuing a tsunami warning.
The RCMP confirmed Wednesday it had executed a search warrant at an address registered to GC Strategies. This development comes as MPs are enacting an extraordinary, rarely used parliamentary power, summoning one of its contractors to appear before the House of Commons to be admonished publicly for failing to answer questions related to the ArriveCan app.
In their 2024 budget, the federal government wants to amend the Canada Labour Code, so employers in federally regulated sectors will eliminate work-related communication with employees outside of scheduled hours. If implemented, this would affect roughly 500,000 across the country.
The federal government says that it will be providing Canada's spy agency with hundreds of millions of dollars over the next eight years, including money to enhance its presence in Toronto in the face of mounting global threats.
Progress has been made on a new compensation model for family doctors, with the Alberta Medical Association (AMA) hopeful for a fall rollout.
Public Health Ontario workers say the potential closure of six laboratories across the province would be dangerous and increase inequity in northern Ontario.
British Columbia’s decriminalization pilot project has been a key topic of discussion at various levels of government in recent weeks, with the conversation re-igniting after comments about diversion by a high-ranking officer of the Vancouver Police Department.
More than 5,500 years ago, two women were tied up and probably buried alive in a ritual sacrifice, using a form of torture associated today with the Italian Mafia, according to an analysis of skeletons discovered at an archeological site in southwest France.
There are a lot of risks when it comes to adolescents using screens — and a new multinational study shows weight-related bullying may be among them.
An experimental error led a team of scientists researching bumblebees to make a startling discovery: the insects’ remarkable ability to survive underwater for up to a week.
The Sundance Film Festival may not always call Park City, Utah, home. The Sundance Institute has started to explore the possibility of other U.S. locations to host the independent film festival starting in 2027, the organization said Wednesday.
Eight-year-old songwriter Zuri Hamilton from Miramichi, N.B., got to show off her talent on 'The Kelly Clarkson Show' on Monday.
A new Lennon and McCartney collaboration is the last thing anybody expected.
Disneyland employees who perform as many of the theme park’s beloved characters have filed to have a vote on whether to join the Actors’ Equity Association, which represents live performers all over the country, from actors on Broadway to strippers in Los Angeles.
Boeing was the subject of dual Senate hearings Wednesday as Congress examined allegations of major safety failures at the embattled aircraft manufacturer, which has been pushed into crisis mode since a door-plug panel blew off a 737 Max jetliner during an Alaska Airlines flight in January.
Drivers in Eastern Canada face a big increase in gas prices because of various factors, especially the higher cost of the summer blend, industry analysts say.
In Salman Rushdie's first book since the 2022 stabbing that hospitalized him and left him blind in one eye, the author wastes no time reliving the day he thought might be his last.
A Celebrity Apex cruise to the Caribbean this month turned into a rocking Newfoundland kitchen party when hundreds of people from Canada's easternmost province happened to be booked on the same ship.
The one thing 9-year-old Cal Clifford wanted more than anything since he was a toddler was a pet octopus.
Auston Matthews has one more chance to reach a milestone not touched in nearly three decades. The Maple Leafs sniper was unable to score in Tuesday night's 5-2 loss to the Florida Panthers, leaving him stuck on 69 goals for the season.
Former football star and celebrity criminal defendant O.J. Simpson was cremated Wednesday, the lawyer handling his estate said following his death last week at home in Las Vegas at age 76.
Toronto Raptors player Jontay Porter has been handed a lifetime ban from The National Basketball Association (NBA) following an investigation which found he disclosed confidential information to sports bettors, the league says.
Tesla will ask shareholders to reinstate a US$55 billion compensation package for CEO Elon Musk that was rejected by a judge in Delaware this year and to move the electric car maker's corporate home from Delaware to Texas.
Tesla has hit a series of roadblocks, including increased competition and declining sales. The company announced Monday it is slashing 10 per cent of its global workforce.
A driver from London will have to find alternative transportation after an OPP officer clocked them travelling nearly 200 km/h on Highway 401 over the weekend.
When Les Robertson was walking home from the gym in North Vancouver's Lower Lonsdale neighbourhood three weeks ago, he did a double take. Standing near a burrow it had dug in a vacant lot near East 1st Street and St. Georges Avenue was a yellow-bellied marmot.
A moulting seal who was relocated after drawing daily crowds of onlookers in Greater Victoria has made a surprise return, after what officials described as an 'astonishing' six-day journey.
Just steps from Parliament Hill is a barber shop that for the last 100 years has catered to everyone from prime ministers to tourists.
A high score on a Foo Fighters pinball machine has Edmonton player Dave Formenti on a high.
A compound used to treat sour gas that's been linked to fertility issues in cattle has been found throughout groundwater in the Prairies, according to a new study.
While many people choose to keep their medical appointments private, four longtime friends decided to undergo vasectomies as a group in B.C.'s Lower Mainland.
A popular highway in Alberta's Banff National Park now has a 'no stopping zone' to help protect two bears.
B.C. resident Robert Conrad spent thousands of hours on Crown land developing an unusual bond with deer.
A Sudbury woman said her husband was bringing the recycling out to the curb Wednesday night when he had to make a 'mad dash' inside after seeing a bear.
The British Columbia government is encouraging anglers to pack their tackle boxes and head out to a remote lake on Vancouver Island as the province attempts to eradicate an invasive population of sport fish.
B.C.'s police watchdog has finished its investigation into an incident on Vancouver Island, concluding the actions of officers weren't connected to a man's death.
Transit users taking SkyTrain through Burnaby Wednesday experienced several hours of service interruptions due to a medical emergency.
Police say one former and one current employee of Air Canada are among the nine suspects that are facing charges in connection with the gold heist at Pearson International Airport last year.
Several Tim Horton’s customers are feeling great disappointment after being told by the company that an email stating they won a boat worth nearly $60,000 was sent in error.
Video of the moment a suspect left Toronto Pearson International Airport with more than $22 million in gold and cash has been released by police.
Calgary has a new brand and it's looking up.
A Calgary doctor has been charged with fraud after allegedly submitting millions of dollars in false claims to the province.
Ramps leading onto Deerfoot Trail in southeast Calgary will be temporarily closed over the weekend, as crews work to improve the highway.
Ottawa motorists are being warned to expect a big hike in gasoline prices this week, as prices rise to the highest level since August 2022.
Several Tim Horton’s customers are feeling great disappointment after being told by the company that an email stating they won a boat worth nearly $60,000 was sent in error.
Spring 2024 is busy at the Almonte General Hospital's (AGH) birthing unit compared to last year.
Halfway between a family medicine group (GMF) and a hospital, the Quebec government on Wednesday clarified its model for private mini-hospitals that will focus on the needs of seniors.
A former Montreal resident was sentenced earlier this week to 10 years in a United States federal prison for a multi-decade fraud that manipulated more than one million Americans into sending money to fake psychics.
Greg Kelley, the Quebec Liberal Party's critic for relations with English-speaking Quebecers, spoke to CTV News about how the CAQ has been handling the English file and what's in store for his own opposition party.
Progress has been made on a new compensation model for family doctors, with the Alberta Medical Association (AMA) hopeful for a fall rollout.
Edmonton-based Flair Airlines released a report Wednesday that included environmental, efficiency and sustainability initiatives, some it hopes to share across the aviation industry.
With the Edmonton Oilers locked into their National Hockey League playoff position, some players will get some game time off — with others scoring opportunities.
The RCMP says it is investigating a sudden death in Nova Scotia’s Colchester County.
Drivers in Eastern Canada face a big increase in gas prices because of various factors, especially the higher cost of the summer blend, industry analysts say.
A Celebrity Apex cruise to the Caribbean this month turned into a rocking Newfoundland kitchen party when hundreds of people from Canada's easternmost province happened to be booked on the same ship.
A motion filed by the man accused of killing four Indigenous women in Winnipeg to have one of those murder charges quashed has been dismissed by the judge – weeks before the start of his trial.
Though spring may be here, parts of Manitoba are set to get a blast of winter weather this week.
Though Winnipeg is full of hardcore hockey lovers, there’s one man who says he’s the Winnipeg Jets biggest fan.
A Regina man who says he was given two hours to vacate the seniors' home he lived in after being evicted should not have been forced to move in the first place.
A 36-year-old man who was an inmate at the Regina Correctional Centre (RCC) was found dead on Tuesday morning, a news release from the province said.
Tuesday night in government committee saw the Ministry of Social Services release documents revealing how much funding was sent to two Regina motels associated with Sask. Party MLA Gary Grewal.
The Waterloo Region Police Services Board wants to explore new ways of dealing with an annual unsanctioned St. Patrick’s Day street party in Waterloo’s University District.
Police say one former and one current employee of Air Canada are among the nine suspects that are facing charges in connection with the gold heist at Pearson International Airport last year.
A Toronto man is facing weapons and other charges after allegedly pulling out a hammer to avoid paying a bar tab in Guelph.
A former massage therapist who pleaded guilty to a string of sexual assaults has had his day parole revoked.
Concern is growing for Saskatoon's homeless population with a core neighbourhood shelter set to close in days.
Motorists in Saskatoon are advised to drive cautiously, with roads wet and slushy following a night of rain and now.
In a lengthy council meeting Tuesday night, city council in Sudbury unanimously voted to build a new arena and events centre downtown.
A former girlfriend of a murder suspect in Sudbury testified Wednesday that he talked about his role in the deaths a day after a firebombing that killed three people.
The body of a missing man has been found after his vehicle was pulled into a northern creek on Saturday morning, Ontario Provincial Police say.
It’s not every day that a new washroom becomes the talk of the town. But in the Lake Huron tourist community of Grand Bend a new so-called smart washroom has many residents and business owners flush with joy.
A full house of concerned citizens turned out to the latest meeting about the future of the Clinton Public Hospital and its overnight emergency room closure.
The hockey community in Chatham-Kent and beyond is mourning the sudden death of a player caught in a highway crash this week in London.
Tim Hortons Roll Up The Rim contest may be in hot water yet again after several customers received emails falsely congratulating them on winning the Tracker boat.
A multi-vehicle collision involving a semi-truck snarled traffic in Barrie on Wednesday afternoon.
One person was taken to the hospital after their vehicle rolled into a drainage creek off Highway 400 in Barrie.
The hockey community in Chatham-Kent and beyond is mourning the sudden death of a player caught in a highway crash this week in London.
Parents of children with learning disabilities are seeking 'certainty' on the long-term status of a program that provides tailored special education support in language and math within schools.
Windsor police have issued an arrest warrant for a 24-year-old man related to an alleged sexual assault of a minor.
The British Columbia government is encouraging anglers to pack their tackle boxes and head out to a remote lake on Vancouver Island as the province attempts to eradicate an invasive population of sport fish.
Construction workers are poised to start building a BC Cancer centre in Nanaimo in 2025 – bringing access to critical treatment services closer to home for thousands of people on Vancouver Island.
Police in Metro Vancouver say their investigation into how a vehicle ended up at the bottom of the Fraser River has led to the discovery of other submerged vehicles, including a school bus and at least two stolen cars.
British Columbia is planning to add 240 new units to its complex-care housing program, providing homes for people with mental-health and addictions challenges that overlap with other serious conditions.
More than 80 residents from a low-income apartment building in Kelowna, B.C., have learned they won't be able to return to their homes for at least another two weeks.
Mounties are investigating a reported "road rage" incident in Kelowna, B.C., that left two men injured last week.
Lethbridge police have arrested a Vermilion, Alta., man in connection with a 'grandparent scam' that took aim at a local senior.
A serious multi-vehicle crash closed a highway north of Coaldale, Alta., on Wednesday morning.
With or without federal support, improvements to a major southern Alberta highway continue because of its critical economic importance as an east-west corridor, the province says.
For the next several months, the City of Sault Ste. Marie will be cracking down on people who improperly use accessible parking spaces.
A suspect riding a bicycle on Gibbs Street in Sault Ste. Marie this week has been charged with assaulting police, along with drug-related offences.
Police in Sault Ste. Marie charged a 26-year-old woman with several offences following an incident Monday morning.
A Celebrity Apex cruise to the Caribbean this month turned into a rocking Newfoundland kitchen party when hundreds of people from Canada's easternmost province happened to be booked on the same ship.
A pricing agreement has been reached between crab fishers and seafood processors that will allow for Newfoundland and Labrador's annual crab fishery to get started.
Longliners across Newfoundland and Labrador are tied up once again, as a new protest by the province's fish harvesters threatens to derail the crab fishery for a second straight year.
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