WHO recommends new COVID-19 shots should target only XBB variants
A World Health Organization (WHO) advisory group on Thursday recommended that this year's COVID-19 booster shots be updated to target one of the currently dominant XBB variants.
New formulations should aim to produce antibody responses to the XBB.1.5 or XBB.1.16 variants, the advisory group said, adding that other formulations or platforms that achieve neutralizing antibody responses against XBB lineages could also be considered.
The group suggested no longer including the original COVID-19 strain in future vaccines, based on data that the original virus no longer circulates in human beings and shots targeting the strain produce "undetectable or very low levels of neutralizing antibodies" against currently circulating variants.
COVID-19 vaccine makers like Pfizer/BioNtech, Moderna Inc and Novavax Inc are already developing versions of their respective vaccines targeting XBB.1.5 and other currently circulating strains.
The U.S. Food and Drug Administration is also set to hold a meeting of outside experts in June to discuss the strain compositions of COVID-19 shots for later this year; vaccine manufacturers will be expected to update their shots once the strains are selected.
The bivalent booster shots developed and distributed last year targeted two different strains - the Omicron variant as well as the original virus.
WHO's advisory group, which recommends if changes are needed to the composition of future COVID-19 shots, said currently approved vaccines should continue to be used in accordance with the agency's recommendations.
In late March, WHO had revised its COVID-19 vaccination recommendations and suggested healthy children and adolescents might not necessarily need a shot, but older and high-risk groups should get a booster between six and 12 months after their last vaccine.
The latest recommendations come about two weeks after WHO ended the global emergency status for COVID-19.
CTVNews.ca Top Stories

Homeowners brace for mortgage payment shock amid higher-for-longer rate outlook
From ultra-low interest rates that led to a huge spike in real estate demand to the speed with which interest rates shot up to levels not seen in a generation, it's been hard to keep up with the shifting landscape for mortgage holders.
McDonald's, Wendy's defeat lawsuit over size of burgers
McDonald's and Wendy's have defeated a lawsuit accusing them of deceiving hungry diners by exaggerating the size of their burgers.
New study shows where you fall on new internet addiction spectrum
Researchers have come up with categories for people who are addicted to the internet and for those who are at risk.
Trump seethes through the start of trial in New York lawsuit accusing him of lying about his wealth
Aggrieved and defiant, former U.S. president Donald Trump sat through hours of sometimes testy opening statements Monday in a fraud lawsuit that could cost him control of Trump Tower and other prized properties.
Diwali fireworks advisory issued despite warnings it might be discriminatory: emails
An Environment Canada advisory that singled out Diwali fireworks as a reason to prepare for poor air quality last October was issued despite multiple warnings from some staff about it being discriminatory.
Federal ministers still lack mandate letters, two months after majority shuffled
Prime Minister Justin Trudeau has yet to issue mandate letters for his cabinet ministers, two months after announcing an overhaul to his front bench.
Grizzly bear attacks rare, but a risk in wilderness, experts say after Banff deaths
Grizzly bear experts say fatal attacks are extremely rare, but it's always a risk when people venture into the wilderness.
Venus may be choked in toxic clouds, but lightning could be a rare sight there, new data suggests
We know the second planet from the Sun to be an inhospitable place, cloaked in thick, yellow clouds of sulfuric acid – but according to a new study, a hypothetical trip to Venus might not be full of thunder and lightning.
Before and after: Damage in wake of Canada's wildfires seen from space
Images captured by satellite show that the damage left in the wake of some of Canada's worst wildfires.