BREAKING Bob Cole, veteran CBC broadcaster and former voice of 'Hockey Night in Canada,' dead at 90
Bob Cole, legendary CBC broadcaster and former voice of Hockey Night in Canada, has died. He was 90.
Researchers at Brigham and Women’s Hospital in Boston are testing an Alzheimer's vaccine on people.
The nasally administered vaccine, called Protollin, is being tested on a group of 16 people with early Alzheimer's disease, between the ages of 60 to 85 years.
Alzheimer's is a cognitive disease that impairs a memory, thought, and language. It is the most common type of dementia. In 2020, 569,600 Canadians were living with dementia.
"This (vaccine) is using some proteins to stimulate the body's own immune cells to clear away the beta-amyloid, which is really the problematic protein in Alzheimer's disease," Dr. Tanuja Chitnis, a neurologist with Brigham and Women’s Hospital, told CTV's Your Morning on Friday.
Amyloid is a protein that builds up in organs and can affect the heart, kidneys, liver, and nervous system.
The vaccine is showing positive results, but more testing is needed to understand dosages and any implications.
"We found that this drug is safe and well-tolerated," Chitnis said. "We're currently working on immunological studies to prove that the vaccine works in the way that we think it does."
If successful, this vaccine could drastically change the lives of people living with Alzheimer's, Chitnis said, allowing anyone to easily administer the drug. The Alzheimer Society of Canada says about 1 in 5 people have experienced caring for someone living with dementia.
"Our results suggested quite safe and patients with early Alzheimer's disease, and we're hoping that it will prevent patients from progressing into those later and more problematic stages of disease in which they can't take care of themselves," Chitnis said.
Another Alzheimer's vaccine has concluded trial results from the U.K., where a randomized placebo-controlled study showed there was a 27 per cent less decline in memory after 18 months.
Chitnis believes more research on Alzheimer's vaccines is "very exciting."
"We're seeing a lot of new treatments for Alzheimer's disease," she said. "Our approach is somewhat different, again, using the body's own immune cells to actually activate and clear away amyloid."
When asked about the trial, Joshua Armstrong, a research scientist with the Alzheimer Society of Canada, said the group would be watching for results.
"This vaccine-like approach of using a nasal spray to activate the body's immune system is a novel and innovative way of potentially addressing the beta amyloid plaques that build up in the brains of people living with Alzheimer's disease," Armstrong said in an email to CTVNews.ca Friday.
"If this treatment passes this Phase 1 trial, which examines the safety and tolerability in just 16 individuals with early-stage Alzheimer's disease, we will be following the future trials of Protollin to see if they result in the reduction of amyloid plaques and the slowing or reversal of cognitive decline in a larger group of patients."
Bob Cole, legendary CBC broadcaster and former voice of Hockey Night in Canada, has died. He was 90.
New York's highest court on Thursday overturned Harvey Weinstein's 2020 rape conviction, reversing a landmark ruling of the #MeToo era in determining the trial judge improperly allowed women to testify about allegations against the ex-movie mogul that weren't part of the case.
Honda is set to build an electric vehicle battery plant next to its Alliston, Ont., assembly plant, which it is retooling to produce fully electric vehicles, all part of a $15-billion project that is expected to include up to $5 billion in public money.
MPP Sarah Jama was asked to leave the Legislative Assembly of Ontario by House Speaker Ted Arnott on Thursday for wearing a keffiyeh, a garment that is banned at Queen’s Park.
A rural Manitoba school trustee is facing calls to resign over comments he made about Indigenous people and residential schools earlier this week.
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Residents of John D'Or Prairie, a community on the Little Red River Cree Nation in northern Alberta, were told to take shelter Thursday morning during a police operation.
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At 6'8" and 350 pounds, there is nothing typical about UBC offensive lineman Giovanni Manu, who was born in Tonga and went to high school in Pitt Meadows.