MESA, Ariz. - Michael Phelps is 0 for 1 in his comeback to the pool.

The 22-time Olympic medallist lost to Ryan Lochte in the 100-metre butterfly final at the Arena Grand Prix on Thursday night.

Lochte touched first in 51.93 seconds, second-fastest in the world this year. Phelps took second in 52.13 in his first meet since retiring after the 2012 London Olympics.

Phelps is the three-time Olympic champion and current world record-holder in the event. His time tied for fourth-quickest in the world.

Olympian Jason Dunford of Kenya finished third in 53.08.

Phelps was faster in the final than he was in winning his preliminary heat with a time of 52.84.